Cell Division and Cancer Risk is one of a series of Data Point resources from HHMI Biointeractive. Data Points engage students in analyzing and interpreting data from primary literature in the biological sciences. The resources are intended to provide authentic phenomena to spark student discussion and exploration, but they can also serve as three-dimensional assessment items. In this example, students analyze a scatter plot that represents the relationship between the number of stem cell divisions in human tissues and the lifetime risk of cancer in those tissues. The authors calculated cancer risk based on previously published studies and estimated stem cell divisions based on the number of cells and cell turnover rate in each tissue. The primary source for this Data Point may be found at: http://science.sciencemag.org/content/347/6217/78. (Free registration with AAAS is required for access to this link.)